enogene/MG-132蛋白酶体抑制剂/E1B1748
市场价：
¥1300.00
美元价：
650.00
产品分类：
酶抑制剂
公司分类：
Enzyme_Inhibitors
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MG-132 Proteasome InhibitorPDF
Catalog Number:
E1B1748Amount:
PHYSICAL APPEARANCE: White solid (m.p. 120-121°C)MOLECULAR FORMULA: C26H41N3O5
Molecular Weight:
475.6Purity:
98% (TLC: 10%MeOH/methylene chloride; Rf = 0.33). Peptide content: 100%Solubility:
Soluble in: DMSO (25 mg/ml); Ethanol (25 mg/ml)Storage/Stability:
Store, as supplied, at -80°C for up to 2 years. May be stored at -20°C for up to 1 week. Store solutions at -80°C for up to 2 months.Recommended Dilutions:
A potent, cell permeable and selective proteasome inhibitor (Ki = 4 nM). Inhibits NF-κB activation by preventing NF-κB degradation (IC50 = 3 μM). Blocks degradation of short-lived proteins, which in turn induces HSP and ER chaperone expression, leading to thermotolerance (1 μM MG-132, 2 h.). Stimulates neurite outgrowth in PC12 cells (20 nM optimal). IC50’s for inhibition of Suc-LLVY-AMC and Z-LLL-AMC cleaving activities of proteasome were 0.85 and 0.1 μM respectively.References:
1 J.Adams and R.Stein Ann.Rep.Med.Chem. 1996 31 2792 K.T.Bush et al. J.Biol.Chem. 1997 272 90863 S.Tsubuki et al. J.Biochem.(Tokyo) 1996 119 572The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.Price:
65$
品牌介绍
enogene的β-actin小鼠单克隆抗体（A02）PDF目录编号：E12-045量：100微克/ 100微升克隆编号：A02背景：β-肌动蛋白是已鉴定出的六种不同的肌动蛋白同工型之一。在各种物种和组织的细胞中发现的肌动蛋白分子在免疫学和物理特性方面趋于非常相似。因此，针对β-肌动蛋白的抗体可用作蛋白质印迹的上样对照。但是，应注意，β-肌动蛋白的水平在某些细胞中可能不稳定。例如，β-肌动蛋白在脂肪组织中的表达非常低，因此不应将β-肌动蛋白用作这些组织的负荷控制。抗体形式：pH 7.4、150mM NaCl，0.02％叠氮化钠和50％甘油的磷酸盐缓冲盐水（不含Mg2 +和Ca2 +）中的小鼠IgG1。储存/稳定性：-20℃/ 1年保存特异性/敏感性：抗体可以检测内源性β-肌动蛋白。反应性：H，R，M，Mk，Dg，Ch，Hm，Rb，Pg，Sh应用范围：WB：1：5,000-10,000 IHC：1：200 IF：1：200
联络我们
